BACK TO: DIAGNOSIS
Dr Stephen Strum and Donna Pogliano, a prostate cancer activist, co-authored a
wonderful source of very detailed information on prostate cancer. It is not an
'easy read' to glance through while lounging by the pool, but it allows laypeople
to get a good understanding of complex medical issues. The full title of the book
is A Primer on Prostate
Cancer. The Empowered Patients Guide. The ISBN number is 0-9658777-6-0
and it has been available at Amazon and Barnes & Noble as well as at the Life
Extension Foundation site, whose support saw the book published.
Strum also provides an excellent service on the Physician
To Patient mailing list. When responding to queries on that List he
Gleason score is a critical item; it is used as a variable in virtually every
prognostic and treatment algorithm. An accurate GS mandates an expert pathology
opinion from a PC pathology expert.
ones that I am most familiar with include:
Germany); Tel: +49-30-8331802 or
 214-6628 Ronald
J. Cohen (Western Australia) [61 8 9386 9888]; email@example.com
Epstein (Hopkins)  955-5043
or 410-955-2162 (Dr. Epstein does not do ploidy analysis)
313-745-2520 Scott Lucia 303-724-3470
Dr.Jonathan Oppenheimer, Prostate Pathologist. Oppenheimer
Urologic Reference Laboratory (Tennessee]  868-7522
second opinion on the microscopic pathology is usually covered by insurance but
if not, runs about $500 pending on what is done. A copy of the original pathology
report with the actual slides or recuts from the tissue
blocks are sent to the outside reviewer. My preference is to request that tissue
blocks be sent to the expert reviewer to optimize the recuting
process. Your primary care doctor or you can initiate such a 2nd opinion but you
need to request this and ask for a specific physician or lab to be used.
other prognostic tests such can be extremely helpful to plan therapy. These tests
are done using IHC (immunohistochemistry)
and include: AMACR, AZGP1, AR, BCL-2, CGA, COX-2, EGF-R, FAS, HER2/Neu, HSP-27, MIB-1, MUC-1, PAP, PSA, p27, p53,
Somatostatin, D2-40. Ploidy analysis
can also be done by some of the above pathologists using the tissue blocks. There
are extra fees for these services.
me, the most detailed and comprehensive pathology review is done by Helmut Bonkhoff
in Berlin, Germany. Also, I know when pathology material is sent to him that he
reviews the material and not an unknown associate using his name.
advice indeed, provided you can find a local urologist or oncologist who can interpret
the reports - for more on Dr Benthoff go along to Bob
Parson's Pathology 101.